In another investigation with T2DM subjects, the overall postprandial iAUC for plasma glucose, ghrelin, and hunger scores were reduced, and greater postprandial overall AUCs for plasma insulin, C-peptide, GLP-1, and satiety scores were noted for a whey protein-based breakfast than for a high-carbohydrate breakfast [342]. This evidence concerns the gene INS and type 2 diabetes mellitus.