Interestingly, it was found that even though whey protein can reduce postprandial TG, FFA, and glucose responses more than casein, cod, and gluten protein in a supplemented fat-rich meal without eliciting plasma insulin, glucagon, GLP-1, and GIP in individuals with T2DM, the retinyl palmitate response in the chylomicron-rich fraction was lower; whereas the retinyl palmitate response in the chylomicron-poor fraction was higher with whey protein than with casein protein and cod protein in the fat-rich meal. This evidence concerns the gene INS and type 2 diabetes mellitus.