Astaxanthin treatment in DSS-induced colitis mice downregulated the cytoplasmic level of 8-hydroxy-2′-deoxyguanosine (8-OhdG), iNOS, and myeloperoxidase (MPO) in colon tissue while upregulating T-superoxide dismutase (T-SOD), which protects the mitochondria by removing uncharged H2O2 into the cytosol [91,161]. This evidence concerns the gene MPO and colitis.