TKS4 deletion or mutation in humans results in the appearance of a hereditary disorder known as FTHS [4,5,6], which is characterized by abnormal growth, skeletal abnormalities, and changes in facial features such as a large cornea, a flattened back of the head, a large cheek, and a small chin [7]. This evidence concerns the gene SH3PXD2B and Frank-Ter Haar syndrome.