Once activated, mTORC1 phosphorylates its effector 70kDa ribosomal protein S6 kinase (p70S6K) and eukaryotic translation initiation factor 4E-binding protein 1 (4E-BP1), thereby initiating processes such as transcription, proliferation, growth, and protein synthesis in tumor cells [20]. This evidence concerns the gene EIF4EBP1 and neoplasm.