For instance, epithelial cells are enriched in the upper-middle part of the slice, consistent with the high expression of its marker gene KRT14 in that region; tumor cells mainly concentrate at the top and middle-lower parts of the slice, with sparse clustering in other areas, aligning with the expression trend of the LGASL1 gene in that region; melanocytes, with fewer in number, are minimally enriched at the far right of the slice, where its marker gene DCT shows high expression, undetectable or at very low levels in other spatial points (Figure 3C). Here, DCT is linked to neoplasm.