Williamson and colleagues demonstrated the existence of rare subpopulations of CTCs co-expressing epithelial cadherin (E-cadherin) and some cytokines typical of VM in patients with SCLC [42], thus stating that higher levels of VM are associated with worse overall survival in patients with limited-stage SCLC (p < 0.025), an event likely due to the increased access of CTCs to the circulation [42]. Here, CDH1 is linked to small cell lung carcinoma.