KIF11 and hepatocellular carcinoma: In HCC cells, KIF11 is targeted by ASPM, and overexpressed KIF11 restores the inhibiting effect on the expression of β-catenin and phosphorylated GSK-3β, which result from the knockdown of ASPM, showing the upregulation of the Wnt signaling pathway and the promotion of proliferation-associated proteins [164].