DKK3 and Familial prostate cancer: For example, hsa_circ_0006404 (which Lin et al. found to be overexpressed in BC plasma compared to healthy plasma [66]) stimulates the progression of hepatocellular carcinoma (HCC) by sponging miR-624 [112], the progression of prostate cancer (PC) via the miR-1299/CFL2 [113] and miR-29a-3p/SLC25A15 axis [114], increasing the resistance of ovarian cancer (OC) to docetaxel treatment via the miR-346/DKK3/p-GP axis [115], and inhibiting the progression of colorectal cancer (CC) via the miR-543/LATS1 axis [116].