In the pathophysiology of allergic diseases, cytokines of epithelial origin, the so-called alarmins (damage-associated molecular patterns (DAMPs)), i.e., TSLP, IL-25, and IL-33, triggered by damaging factors (viruses, allergens, and proteases), are involved in the pathophysiology of asthma and atopic dermatitis by activating the immune response in a Th2-dependent manner [55]. Here, IL33 is linked to atopic eczema.