For example, PTEN [33], RBL1 [34], CDKN2AIP [35], RNASET2A [36], HINT1 [37], and PARP12 [38] are well-known tumor suppressors and were downregulated or absent in the CT26/SCID tumors (Table S1). The gene discussed is CDKN2AIP; the disease is neoplasm.