Elevated levels of S100A8/A9 that can be used as potential biomarkers in those diseases were also noticed in other autoimmune or autoinflammatory diseases such as juvenile dermatomyositis, inflammatory bowel disease, Behçet’s disease, polymyalgia rheumatica, cryopyrin-associated periodic syndromes, etc. [4,10,13], which makes us believe that the results of our study were not accidental. The gene discussed is NLRP3; the disease is inflammatory bowel disease.