Cellular host responses, including C-reactive protein (CRP), procalcitonin (PCT), whole blood counts, erythrocyte sedimentation rate (ESR) and acute phase cytokines (TNF, IL-8, IL-6, etc.), have all been inconsistent in terms of their discriminatory power for identifying sepsis and cannot discriminate between causative organisms [28,29,30,31,32,33]. This evidence concerns the gene IL6 and Sepsis.