The exclusion criteria were the following: the lack of understanding German or Norwegian language, pregnancy, breastfeeding, allergy to the active substances/excipients used in the study, the presence of prolactin-dependent tumors, phaeochromocytoma, concomitant use of drugs that could induce torsades de pointes (heart disease), levodopa use, and high risk of narrow-angle glaucoma [40]. This evidence concerns the gene PRL and allergic disease.