IGFBP2 and psychiatric disorder: A case report of a woman with treatment-resistant schizophrenia, who was found to have the 15q11.2 BP1-BP2 deletion, reminds clinicians to consider the possibility for rare CNVs which may help to explain atypical clinical presentations of severe mental illnesses which have an identifiable genetic origin, and thus help to guide potential treatment implications, available either now or in the future [213].