In comparison to our reported glioma classifier aiming at differentiating among a broad range of primary brain tumors, Quesnel et al. used RS and support vector machine-based analysis to differentiate among different grades of gliomas and between tumors with the IDH1 mutation or IDH wildtype, with reported accuracies between 75% and 85% [34]. This evidence concerns the gene IDH1 and central nervous system cancer.