In line with this, Hao et al. demonstrated that Faecalibacterium prausnitzii (ATCC 27766) exhibited psychobiotic effects by increasing cecal SCFAs and plasma IL-10 levels, and decreasing corticosterone and IL-6 levels in rats with anxiety and depression-like behaviors caused by chronic unpredictable mild stress [230]. Here, IL6 is linked to major depressive disorder.