In the association analysis that was adjusted for age and sex (Table 2), obesity was positively associated with the enzyme activity of CAT (β = 0.05 ± 0.01, p = 5.0 × 10−3) and GPx (β = 0.13 ± 0.01, p = 3.7 × 10−19). The gene discussed is CAT; the disease is obesity due to melanocortin 4 receptor deficiency.