CS and ischemia: Studies have shown that mitochondrial content parameters, as well as pro-fission and pro-fusion parameters, were significantly higher in ischemia-resistant regions (CA2/3 compared to the CA1 region) 24 to 96 h after transient global I/R in gerbils; in ischemia-vulnerable regions, greater neuronal loss and decreased enzymatic activity of citrate synthase was observed [22].