SLC27A1 and steatosis: In this sense, the inclusion of the HT-rich extract in the HFD, similarly to diet restriction, downregulated the gene expression of these molecules (namely lpl, fatp1 and fabp1), indicating a protective role in preventing the development of diet-induced steatosis, as demonstrated in liver FABP-knockout mice fed a high-saturated fat and high-cholesterol diet [46].