Unfortunately, we could not identify serum biomarkers reflecting localized and subclinical choroidal inflammation status in eyes with non-ocular sarcoidosis; Choroidal thickness in the non-ocular sarcoidosis group did not show significant association with CRP (an inflammation marker in various inflammatory systemic diseases) [27–29] or ACE (a biomarker for systemic sarcoidosis, correlated with the granuloma burden and disease severity) levels [30, 31]. The gene discussed is ACE; the disease is ocular sarcoidosis.