The results of the Cox univariate proportional hazards regression showed that age, periodontal condition, body mass index (BMI), clinical stage, T stage, recurrence, tumor size, tumor differentiation, neck dissection, poor oral hygiene habits, P. gingivalis, DOK3, and M2-TAM immunoexpression levels were significantly different (all P < 0.05) (Table 4). The gene discussed is DOK3; the disease is neoplasm.