Our review of the literature revealed that aberrantly expressed IL-10, MIG, and RANTES are all associated with premature atherosclerosis, a devastating consequence of chronic inflammation in the MPN [48–50].MIG binds to the receptor CXCR3 and not only participates in the recruitment of T cells to peripheral sites of inflammation [51]but also chemotactically recruits monocytes/macrophages to sites of inflammation. This evidence concerns the gene CCL5 and myeloproliferative disorder.