There were no significant differences in APACHE II score, lactate, albumin, creatinine, appropriate antimicrobial therapy, special therapy (containing CRRT/ECOMO), percutaneous drainage, recent surgery, underlying disease of malignant tumor, chronic kidney dysfunction, chronic cardiac dysfunction, hypertension, chronic respiratory disease, diabetes, enteral nutrition and history of allergy to antibiotics. This evidence concerns the gene ALB and hypertensive disorder.