TLR3 and neoplasm: Meanwhile, the ferroptosis of tumor cells detected by the ferroptosis-sensitive lipid peroxidation probe C11-BODIPY using flow cytometry also comfirmed that poly(I:C) stimulated CD8+TLR3wt T cells, rather than CD8+TLR3-/- T cells, could significantly induce remarkable more tumor ferroptosis than the PBS-treated CD8+ T cells (P < 0.001, Fig. 6B, bottom panel).