CD8A and hepatocellular carcinoma: As shown in Fig. 5A, T cell infiltration score of T cell subsets in both Tumor1 and Tumor2 were reduced by RT as a whole, while poly(I:C) plus RT could significantly improve infiltration score of T cells, especially CD8+ T cells, in both Tumor1 and Tumor2 of HCC tumor-bearing mice [Tumor1: RT 0.016 ± 0.005 vs Poly(I:C) + RT 0.118 ± 0.016, P = 0.005; Tumor2: RT 0.015 ± 0.005 vs Poly(I:C) + RT 0.079 ± 0.013, P = 0.010].