Of these 19 proteins, five have already been reported in thyroid cancer studies, including galectin-3 (LGALS3)13, chromogranin-A (CHGA)14, collagen alpha-3(VI) chain (COL6A3)15, collagen alpha-1(XXIII) chain (COL23A1)16, and integrin alpha-4 (ITGA4)17. This evidence concerns the gene ITGA4 and thyroid gland carcinoma.