Using published data from this study, we aimed to clone and express PVRL and PCNSL BCRs from available immunoglobulin heavy chain variable region (IGHV) and immunoglobulin light chain variable region (IGLV) DNA sequences as Fabs to test for SAMD14/neurabin-I reactivity of PCNSL cases and to test for specific binding of PVRL Fabs against human antigens. Here, SAMD14 is linked to primary central nervous system lymphoma.