Living in a high or low AP region of the Czech Republic was a significant predictor for brain-derived neurotrophic factor (BDNF) (M (IQR) for MS and SB Regions: 23.7 (18.6; 29.3) ng/ml and 24.8 (19.5; 30.3) ng/ml) with lower values in the Moravian-Silesian (high AP) Region (Tables 5, S6). This evidence concerns the gene BDNF and myeloid sarcoma.