Strikingly, Prox1 expression has been noted in rod progenitors as well as the Müller glia cells in the fish70, while high co-expression of RGC markers was reported recently in the proliferating cones of retinoblastoma pluripotent stem cell derived organoids as well as patient retinoblastoma samples71,72. The gene discussed is PROX1; the disease is retinoblastoma.