Oral treatment with Pyrazolpyridine KDU731 significantly reduced intestinal infection and oocyst shedding in a IFN-γ KO mice model (treated 7 days post infection with a dose of 10 mg/kg for 1 week) and neonatal calves (treated 4 days post infection with 5 mg/kg every 12h for 7 days). Here, IFNG is linked to infection.