AFP and cancer: However, cystic mature teratomas grow slowly, with an average growth rate of 1.8 mm/year in premenopausal women,[1] and most patients are unable to identify the size and location of the tumor by physical examination; We usually need color Doppler ultrasonography, CT and MRI to help us evaluate the size, extension direction of pelvic tumors and their anatomical relationship with surrounding tissues and organs, and then preliminarily determine the benign and malignant tumors by serum tumor markers: alpha-fetoprotein, CA-199, HE4, and CA-125.