CHGA and neuroendocrine neoplasm: CgA, a biomarker for neuroendocrine tumors,[95] is an acidic glycoprotein that generates various biologically active peptides upon intragranular or extragranular hydrolysis, including the peptides CgA1-76 (vasostatin-I), CgA1-113 (vasostatin-II), CgA79-113 (vasoactive inhibitory peptide, VIP), CgA250-301 (pancreastatin), CgA352-372 (catestatin), CgA411-436 (serpinin), and more.[96] Studies on the substance and metabolism of CgA and its components mainly focus on pancreatin (PST).