A research indicated that OSA patients who responded to continuous positive airway pressure treatment exhibited more pronounced improvement of lobular inflammation on liver biopsy than those who did not respond.[21] Moreover, OSA treatment resulted in the decrease of circulating sCD163 and a trend toward an increase in sFasL.[22] Both were markers of hepatocyte apoptosis and Kupffer cell activation. The gene discussed is CD163; the disease is obstructive sleep apnea syndrome.