ALDH1A3 and cancer: Our previous study showed that ALDH1A3 expression is highly upregulated by treatment with cytotoxic anticancer drugs such as 5-FU, 7-ethyl-10-hydroxycamptothecin (also known as SN-38), cisplatin (CDDP), and paclitaxel in gastric cancer patient-derived cells (PDC) and is involved in cancer cell survival (19).