Pooled results of cohort studies also did support a protective role of angiotensin converting enzyme inhibitors (ACEIs) (OR = 0.97, 95%CI = 0.89–1.07) users and angiotensin II receptor blockers (ARBs) (OR = 0.8, 95%CI = 0.63–1.02) in PD. The gene discussed is ACE; the disease is Parkinson disease.