Post-AKI development of fibrosis from maladaptive cell repair may lead to increased renin and salt-sensitivity, which may be better captured by BP abnormalities, rather than CKD measures, which are affected by renal reserve.48 Future research should explore renin-angiotensin-aldosterone system abnormalities in the AKI to CKD pathogenesis after cisplatin. Here, REN is linked to chronic kidney disease.