Similarly, in a murine model of lipopolysaccharide (LPS)-induced acute lung injury (ALI), α-tocopherol lowered the expression of pro-inflammatory cytokines and increased the expression of the antioxidant molecules superoxide dismutase (SOD)1/2 and glutathione peroxidase (GSH-Px) [40]. This evidence concerns the gene SOD1 and acute lung injury.