Our results showed that 33 differentially expressed lncRNAs in IPF fibroblasts could regulate the ten hub mRNAs, as demonstrated by the co-expression network from which the five lncRNAs with the highest interaction were selected identifying AC008708.1, AC091806.1, AL442071.1, FAM111A-DT, and LINC01989, whose biological functions are poorly understood and currently none have been previously associated with fibrosis. Here, LINC01989 is linked to idiopathic pulmonary fibrosis.