SLC27A5 and fatty liver disease: Z-ligustilide and n-Butylidenephthalide in the aqueous extract from Angelica tenuissima inhibited high-fat diet-induced hepatic steatosis in mice and oleic acid-induced lipid accumulation in HepG2 cells, which were correlated with downregulated CD36 and FATP5 and thus reduced lipid uptake [265].