ACTA1 and infection: Compared with that in the control group, the expression of mRNA of collagen I and α-SMA in the liver in mice 6, 8, and 10 weeks after infection had significantly increased (p < 0.0001, p < 0.0001), and the expression of collagen III had significantly increased at 10 weeks after infection (p < 0.0001) (Figure 3C).