The first component was histologically a germinoma component (Figure 2a), consisting of large, round tumor cells staining for placental alkaline phosphatase (PLAP) (Figure 2d) and mixed with small lymphocytes, and an embryonal carcinoma-like component (Figure 2b,c), which showed epithelial features and calcification (Figure 2b), as well as immunoreactivity for cytokeratin and partly for AFP (Figure 2e) and CD30 (Figure 2f). The gene discussed is AFP; the disease is embryonal carcinoma.