PLCG2 and familial dilated cardiomyopathy: While the majority of patients reported have been case reports of individuals or families, recently, population variants in CLEC7A, encoding the β-glucan pattern recognition receptor DECTIN-1, PLCG2, DUOX1, and DUOXA1 were shown to be overrepresented in an Arizona cohort of DCM patients compared with ancestry-based frequencies in gnomAD or 1000 Genomes datasets [4].