FBN1 and tricuspid valve insufficiency: It included nine clinical parameters, and one molecular parameter: four cardiac features (MVP, mitral regurgitation, tricuspid regurgitation, and aortic root dilatation), five systemic parameters (arachnodactyly, join contractures, pulmonary disease, facial features, and lens dislocation), and an FBN1 variant (variants located within exons 24–32).