NPPB and pulmonary embolism: In patients suffering from PE, haemodynamic status at presentation is the major prognostic factor, while in stable patients, a combination of clinical indices [pulmonary embolism severity index (PESI)], biomarkers [elevated values of troponin (Tn), B-type Natriuretic Peptide (BNP) or N-terminal pro-BNP (NT-proBNP)], and echocardiographic indices of right ventricular dysfunction or pressure overload (RVd/po) have been used to identify those with higher short-term mortality [10,11,12,13,14,15,16].