TFRC and early-onset autosomal dominant Alzheimer disease: An analysis of the Mayo Clinic RNA-seq dataset (syn5550404, Synapse.org; https://www.synapse.org/#!Synapse:syn5550404), which compared 134 patients with Alzheimer’s disease and 130 control subjects, revealed a significant increase in transcripts for the transferrin receptor (TFRC) in the temporal cortex of patients with Alzheimer’s disease [32].