SCN1A and Dravet syndrome: To address this issue and gain a better understanding of the role of microglia in epilepsy, we used a zebrafish genetic model of DS, a severe intractable epileptic syndrome in infants, which is caused in 70–80% of the cases by de novo loss-of-function mutations in the gene encoding the voltage-gated sodium channel, SCN1A [29,30,31].