Our hypothesis is supported by a study of exosomal delivery of annexin A1 (ANXA1) by medullary thyroid carcinoma SW579 cells, which caused the malignant transformation of Nthy ori3 1 thyroid follicular epithelial cell lines that, subsequently, resulted in an increased levels of proliferation, invasion, and epithelial–mesenchymal transition [62]. The gene discussed is ANXA1; the disease is medullary thyroid gland carcinoma.