SYP and neoplasm: CU-PC01 tumours display DNPC-like clinicopathological features, including the absence of AR, PSA and PSMA, loss of PTEN and RB, and a lack of NE markers, including SYP, neuronal differentiation 1 (NEUROD1), POU class 2 homeobox 3 (POU2F3) and achaete-scute homolog 1 (ASCL1).