CEACAM5 and neoplasm: In particular, it has been discovered that TRX1 is closely related with the survival of breast cancer cells [6], and importantly, it is involved in the whole tumor development process, whereas other biomarkers such as carcinoembryonic antigen (CEA) and cancer antigen 15-3 (CA15-3) can only be found in overstated tumors [7,8].