TRDN and catecholaminergic polymorphic ventricular tachycardia: CPVT has been classified based on the gene pathogenic variant into five subtypes: CPVT1, which involves the RyR2 gene with autosomal dominant transmission, is responsible for approximately 60% of cases; CPVT3, which involves the TRDN gene with autosomal recessive transmission, manifests around the age of 10 age; CPVT2 involving the CASQ2 gene with autosomal recessive transmission manifests around seven years of age; and CPVT4 involving the ANK2 gene and CPVT5 involving the KCNJ2 gene are autosomal dominant and manifest at 4 and 2.5 years of age and with a frequency of <1% (Figure 3) [50,51].