Logistic regression analysis of CSF immunoglobulins and TBM prognosis showed that IgG [odds ratio (OR) = 4.796, 95% confidence interval (CI): 2.575–8.864], IgM (OR = 3.456, 95% CI: 2.757–5.754), and IgA (OR = 4.371, 95% CI: 2.731–5.856) were TBM risk factors for poor prognosis in patients. Here, CD79A is linked to meningeal tuberculosis.